Tunable nanostructured biochip substrates for enhanced detection. Brochure includes table of capabilities for biosensor fabrication.
Moxtek has achieved low cost, wafer-scale manufacturing of photonic crystal, plasmonic and other hybrid structures. Here the application of TiO2 photonic crystal guided-mode resonance structures for label-free sensing and microarray based surface enhanced fluorescence based detection is presented. The structures exhibited an average 7.7 fold fluorescence enhancement over a reference glass slide for Human IgG, IgM, IgA, and streptavidin-biotin assays and also exhibited a 2.5nm spectral shift following the attachment of a self-assembled monolayer, thereby exhibiting the capability for detecting sub-monolayers thicknesses.
Moxtek has developed cost effective and reliable methods to obtain uniform wafer scale metallic nanohole array patterned biochips. Here their use as fluorescence enhancing substrates for Cy3 based protein microarrays is demonstrated. The structures, utilizing highly focused and enhanced optical fields, greatly boost the fluorescence SNR, allowing for the detection of antigen concentrations 3+ orders of magnitude lower than current commercial standards.
Moxtek has developed cost effective and reliable methods to obtain uniform wafer scale metallic and dielectric nanohole, nanopost, nanodome, and photonic crystal arrays. These can serve as optical biochip platforms for applications such as enhanced fluorescence, surface enhanced Raman spectroscopy, and label free sensing. A wide range of structural parameters can be tuned, allowing for customization to your unique needs.
Visit us at SPIE Defense and Commercial Sensing Expo Booth #123 to learn more about our Pixelated and UV polarizers. We will also have a hands-on demonstration of our PBS ICE Cube!
Moxtek is excited to be an exhibitor at Pittcon 2016 in Atlanta, GA. Come see us at booth #4557 !
Visit us at SPIE Photonics West Booth #4240 to experience a hands-on demonstration of our new ICE Cube and enter to win a ProFlux polarizer sample kit!