Aluminum Nanohole Arrays for Highly Enhanced Fluorescence Detection
Emerging Technology · 5/05/16
Moxtek has developed cost effective and reliable methods to obtain uniform wafer scale metallic nanohole array patterned biochips. Here their use as fluorescence enhancing substrates for Cy3 based protein microarrays is demonstrated. The structures, utilizing highly focused and enhanced optical fields, greatly boost the fluorescence SNR, allowing for the detection of antigen concentrations 3+ orders of magnitude lower than current commercial standards.