Fluorescence and label free based detection methods serve as very effective means to identify and detect literally any biomolecule of interest. Though very useful, both methods offer relatively low signal to noise ratios (SNRs). By incorporating metallic nanostructures, which provide highly focused and enhanced optical fields, one can boost the SNR by several orders of magnitude, thereby resulting in a highly enhanced fluorescence response. Furthermore, nanofocusing of the light at the metallic surface allows for label free sensing of target biomolecules. Building on years of expertise, Moxtek has developed inexpensive and reliable methods to obtain uniform wafer scale metallic and dielectric nanostructures that can be used as Biochips for these applications. Additionally, our nanofabrication expertise at Moxtek allows us to also provide numerous photonic crystal based structures. See the PDF here.